The PRIMAGE project, financed by the European Commission, kicked off in December 2018. The 16 European partners are participating in the consortium and the project will run for 4 years.

The partners are internationally recognised researches in in-silico technologies and clinical experts in paediatric cancer. It is one of the largest and more ambitious European research projects in medical imaging, artificial intelligence and childhood cancer.

The PRIMAGE project is devoted to developing methods of computational analysis of medical images applied to childhood cancer. It proposes a cloud-based platform to support decision making in the clinical management of malignant solid tumours, offering predictive tools to assist diagnosis, prognosis, therapies choice and treatment follow up, based on the use of novel imaging biomarkers, in-silico tumour growth simulation, advanced visualisation of predictions with weighted confidence scores and machine-learning based translation of this knowledge into predictors for the most relevant, disease-specific, clinical end points.

The proposed data infrastructures, imaging biomarkers and models for in-silico medicine research will be validated in the application context of two paediatric cancers, Neuroblastoma (NB, the most frequent solid cancer of early childhood) and the Diffuse Intrinsic Pontine Glioma (DIPG, the leading cause of brain tumour-related death in children).

SIOP Europe will draw on its extensive experience with other European projects to coordinate the dissemination Work Package.

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